Article
DNA repair gene XRCC1 polymorphisms and head and neck cancer risk: an updated meta-analysis including 16344 subjects.
PloS one - 1 Jan 2013
Lou Yin, Peng Wen-jia, Cao Dong-sheng, Xie Juan, Li Hong-hong, Jiang Zheng-xuan
Abstract excerpt
BACKGROUND: DNA repair gene X-ray repair cross complementing group 1 (XRCC1) plays an important role in the maintenance of the genomic integrity and protection of cells from DNA damage. Sequence variation in XRCC1 gene may alter head and neck cancer (HNC) susceptibility. However, these results are inconclusive. To derive a more precise estimation of the relationship between XRCC1 polymorphism and HNC risk, we...
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