Article
Detection of XRCC1 gene polymorphisms in Turkish head and neck squamous cell carcinoma patients: a comparative analysis with different populations.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology - 1 Jan 2000
Mutlu Pelin, Mutlu Murad, Yalcin Serap, Unsoy Gozde, Yaylaci Atilay, Saylam Guleser, Akin Istemihan, Korkmaz Hakan, Gunduz Ufuk
Abstract excerpt
PURPOSE: X-ray repair cross-complementing (XRCC1) is one of the most important genes for the maintenance of genomic integrity and protection of cells from DNA damage. Although tobacco and alcohol consumption are the major risk factors for the development of head and neck squamous cell carcinoma (HNSCC), sequence variation in XRCC1 gene may alter HNSCC susceptibility. Reports on the relationship between HNSCC and...
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