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Article

Polymorphisms involving gain or loss of CpG sites are significantly enriched in trait-associated SNPs.

Oncotarget - 24 Nov 2015

Zhou Dan, Li Zhenli, Yu Dan, Wan Ledong, Zhu Yimin, Lai Maode, Zhang Dandan

Abstract excerpt

Some single nucleotide polymorphisms (SNPs) influence the existence of CpG sites, the basis of DNA modification such as methylation and hydroxymethylation. These polymorphisms can lead to gain or loss of CpG sites and were defined as CpG site related SNPs (cgSNPs) in this study. The cgSNPs change DNA sequence and might potentially affect DNA modification such as methylation. However, the functional consequence of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26503467
DOI: 10.18632/oncotarget.5650
PMCID: PMC4741875

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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