Article
Chromatin structure is distinct between coding and non-coding single nucleotide polymorphisms.
BMC molecular biology - 5 Oct 2014
Liu Hongde, Zhai Jinchen, Luo Kun, Liu Lingjie
Abstract excerpt
BACKGROUND: Previous studies suggested that nucleosomes are enriched with single nucleotide polymorphisms (SNPs) in humans and that the occurrence of mutations is closely associated with CpG dinucleotides. We aimed to determine if the chromatin organization is genomic locus specific around SNPs, and if newly occurring mutations are associated with SNPs. RESULTS: Here, we classified SNPs according their loci and...
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