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Article

Structural mechanism of high affinity FcγRI recognition of immunoglobulin G.

Immunological reviews - 1 Nov 2015

Lu Jinghua, Sun Peter D

Abstract excerpt

Antibody-based immunotherapies are becoming powerful means of modern medicine for treating cancers and autoimmune diseases. The increasing popularity of antibody-based treatment demands a better understanding of antibody functions and in particular, their interaction with Fc receptors as effectiveness of antibodies often depends on their ability to activate or avoid effector cell functions through Fc receptors....

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Share to Antibody Affinity
Share to Glycosylation
Share to Immunoglobulin Fc Fragments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoglobulin G

Share to Molecular Docking Simulation

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Share to Protein Interaction Domains and Motifs

Share to Receptors, IgG

Source

Identifiers

PMID: 26497521
DOI: 10.1111/imr.12346

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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