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Article

Neonatal Fc receptor (FcRn): a novel target for therapeutic antibodies and antibody engineering.

Journal of drug targeting - 1 May 2014

Wang Yuan, Tian Zehua, Thirumalai Diraviyam, Zhang Xiaoying

Abstract excerpt

The biomedical applications of antibodies as prophylactics, therapeutics and diagnostics are developing rapidly. Neonatal Fc receptor (FcRn) is a major IgG Fc receptor capable of facilitating the translocation of IgG. FcRn can protect IgG from intracellular catabolism, thereby increasing its half-life. In recent decade, the interaction between FcRn and the Fc region has been reported with the focuses on either...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 24404896
DOI: 10.3109/1061186X.2013.875030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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