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The Influence of Variable-Heavy (V <sub>H</sub> ) Chain Families on IgG <sub>2</sub> , <sub>3</sub> , <sub>4</sub> on FcγRs and Antibody Superantigens Protein G and L Binding using Biolayer Interferometry

2023-03-27

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> As the most abundant immunoglobulin in blood and the most common human isotype used for therapeutic monoclonal antibodies, the engagement and subsequent activation of its Fc receptors by IgGs are crucial for antibody function. While generally assumed to be relatively constant within subtypes, recent studies have shown the antibody variable regions to exert distal effects of...

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Literature Corpus work: 09414ade-f93d-51e9-bfdb-0f312bbd346f
DOI: 10.1101/2023.03.26.534243

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The Influence of Variable-Heavy (V <sub>H</sub> ) Chain Families on IgG <sub>2</sub> , <sub>3</sub> , <sub>4</sub> on FcγRs and Antibody Superantigens Protein G and L Binding using Biolayer InterferometryDOI 10.1101/2023.03.26.534243Read

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