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Deus ex Candida genetics: overcoming the hurdles for the development of a molecular toolbox in the CTG clade

27 Jan 2012

Abstract excerpt

Dominant selectable markers, reporter genes and regulatable systems remain powerful molecular tools for genetic and cell biology studies in fungi. Among Saccharomycotina, it is currently accepted that most species belonging to the genus Candida have adopted a specific codon usage, whereby the CTG codon encodes serine instead of leucine. This group is now widely referred to as the CTG clade. For a long time, this...

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PMID: 22282522
DOI: 10.1099/mic.0.055244-0

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