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Article

Large-scale essential gene identification in Candida albicans and applications to antifungal drug discovery.

Molecular microbiology - 1 Oct 2003

Roemer Terry, Jiang Bo, Davison John, Ketela Troy, Veillette Karynn, Breton Anouk, Tandia Fatou, Linteau Annie, Sillaots Susan, Marta Catarina, Martel Nick, Veronneau Steeve, Lemieux Sebastien, Kauffman Sarah, Becker Jeff, Storms Reginald, Boone Charles, Bussey Howard

Abstract excerpt

Candida albicans is the primary fungal pathogen of humans. Despite the need for novel drugs to combat fungal infections [Sobel, J.D. (2000) Clin Infectious Dis 30: 652], antifungal drug discovery is currently limited by both the availability of suitable drug targets and assays to screen corresponding targets. A functional genomics approach based on the diploid C. albicans genome sequence, termed GRACETM (gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 14507372
DOI: 10.1046/j.1365-2958.2003.03697.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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