Article
Association Analysis of the Reticulon 1 Gene in End-Stage Kidney Disease.
American journal of nephrology - 1 Jan 2015
Bonomo Jason A, Palmer Nicholette D, He John Cijiang, Fan Ying, Hicks Pamela J, Lea Janice P, Okusa Mark D, Bowden Donald W, Freedman Barry I
Abstract excerpt
BACKGROUND: The reticulon 1 gene (RTN1) encodes reticulons, endoplasmic reticulum stress proteins recently implicated in kidney disease progression. METHODS: RTN1 single nucleotide polymorphisms (SNPs) were tested for association with type 2 diabetes (T2D)-associated end-stage kidney disease (ESKD) in African Americans (AAs) and European Americans (EAs), and AAs with non-diabetic ESKD. RTN1 SNPs that were...
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