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Article

Association Analysis of the Cubilin (CUBN) and Megalin (LRP2) Genes with ESRD in African Americans.

Clinical journal of the American Society of Nephrology : CJASN - 6 Jun 2016

Ma Jun, Guan Meijian, Bowden Donald W, Ng Maggie C Y, Hicks Pamela J, Lea Janice P, Ma Lijun, Gao Chuan, Palmer Nicholette D, Freedman Barry I

Abstract excerpt

BACKGROUND AND OBJECTIVES: Genetic variation in the cubilin (CUBN) gene is associated with albuminuria and CKD. Common and rare coding variants in CUBN and the gene encoding its transport partner megalin (LRP2) were assessed for association with ESRD in blacks. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Sixty-six CUBN and LRP2 single-nucleotide polymorphisms (SNPs) were selected and analyzed in this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Low Density Lipoprotein Receptor-Related Protein-2

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Source

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Identifiers

PMID: 27197912
DOI: 10.2215/CJN.12971215
PMCID: PMC4891762

Genes

CUBN
LRP2

Variants

rs1801239
rs17848169

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Association Analysis of the Cubilin (CUBN) and Megalin (LRP2) Genes with ESRD in African Americans.PMID 27197912Read ↗

CUBN is a gene locus for albuminuria.Semantic proximity Read ↗

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Exome wide association study on Albuminuria identifies a novel rare variant in <i>CUBN</i> and additional genes, in 33985 Europeans with and without diabetesSemantic proximity Read ↗

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Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function.Semantic proximity Read ↗

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