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Genome-wide association study of hospitalized patients and acute kidney injury.

Kidney international - 1 Aug 2024

Siew Edward D, Hellwege Jacklyn N, Hung Adriana M, Birkelo Bethany C, Vincz Andrew J, Parr Sharidan K, Denton Jason, Greevy Robert A, Robinson-Cohen Cassianne, Liu Hongbo, Susztak Katalin, Matheny Michael E, Velez Edwards Digna R

Abstract excerpt

Acute kidney injury (AKI) is a common and devastating complication of hospitalization. Here, we identified genetic loci associated with AKI in patients hospitalized between 2002-2019 in the Million Veteran Program and data from Vanderbilt University Medical Center's BioVU. AKI was defined as meeting a modified KDIGO Stage 1 or more for two or more consecutive days or kidney replacement therapy. Control...

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Identifiers

PMID: 38797326
DOI: 10.1016/j.kint.2024.04.019
PMCID: PMC11260539

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