Article

Key features of the genetic architecture and evolution of host-microbe interactions revealed by high-resolution genetic mapping of the mucosa-associated gut microbiome in hybrid mice

2021-09-28

Abstract excerpt

Determining the forces that shape diversity in host-associated bacterial communities is critical to understanding the evolution and maintenance of metaorganisms. To gain deeper understanding of the role of host genetics in shaping gut microbial traits, we employed a powerful genetic mapping approach using inbred lines derived from the hybrid zone of two incipient house mouse species. Further, we uniquely performed...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 90df30a1-8329-5175-adf7-aaed9ce8df79
DOI: 10.1101/2021.09.28.462095

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Key features of the genetic architecture and evolution of host-microbe interactions revealed by high-resolution genetic mapping of the mucosa-associated gut microbiome in hybrid miceDOI 10.1101/2021.09.28.462095Read

Host genetic determinants of the gut microbiota of wild miceSemantic proximity Read

Using the Collaborative Cross to identify the role of host genetics in defining the murine gut microbiomeSemantic proximity Read

Murine gut microbiota is defined by host genetics and modulates variation of metabolic traits.Semantic proximity Read

Unravelling the effects of the environment and host genotype on the gut microbiome.Semantic proximity Read

Systems genetic discovery of host-microbiome interactions reveals mechanisms of microbial involvement in diseaseSemantic proximity Read

Individuality in gut microbiota composition is a complex polygenic trait shaped by multiple environmental and host genetic factors.Semantic proximity Read

Host genetic and environmental effects on mouse intestinal microbiota.Semantic proximity Read

Using the collaborative cross to identify the role of host genetics in defining the murine gut microbiomeSemantic proximity Read

Genetic mapping of microbial and host traits reveals production of immunomodulatory lipids by Akkermansia muciniphila in the murine gut.Semantic proximity Read

Impact of diet and host genetics on the murine intestinal mycobiomeSemantic proximity Read

Of genes and microbes: solving the intricacies in host genomes.Semantic proximity Read