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Article

Preexisting CD8+ T-cell immunity to the H7N9 influenza A virus varies across ethnicities.

Proceedings of the National Academy of Sciences of the United States of America - 21 Jan 2014

Quiñones-Parra Sergio, Grant Emma, Loh Liyen, Nguyen Thi H O, Campbell Kristy-Anne, Tong Steven Y C, Miller Adrian, Doherty Peter C, Vijaykrishna Dhanasekaran, Rossjohn Jamie, Gras Stephanie, Kedzierska Katherine

Abstract excerpt

The absence of preexisting neutralizing antibodies specific for the novel A (H7N9) influenza virus indicates a lack of prior human exposure. As influenza A virus-specific CD8(+) T lymphocytes (CTLs) can be broadly cross-reactive, we tested whether immunogenic peptides derived from H7N9 might be recognized by memory CTLs established following infection with other influenza strains. Probing across multiple...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24395804
DOI: 10.1073/pnas.1322229111
PMCID: PMC3903243

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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