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Article

Runx2 expression: A mesenchymal stem marker for cancer

23 Sept 2016

Abstract excerpt

The transcription factor runt-related transcription factor 2 (Runx2) is a master gene implicated in the osteogenic differentiation of mesenchymal stem cells, and thus serves a determinant function in bone remodelling and skeletal integrity. Various signalling pathways regulate Runx2 abundance, which requires a number of molecules to finely modulate its expression. Furthermore, this gene may be...

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PMID: 27895787
DOI: 10.3892/ol.2016.5182

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