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Article

RUNX3 in Stem Cell and Cancer Biology.

Cells - 25 Jan 2023

Chuang Linda Shyue Huey, Matsuo Junichi, Douchi Daisuke, Bte Mawan Nur Astiana, Ito Yoshiaki

Abstract excerpt

The runt-related transcription factors (RUNX) play prominent roles in cell cycle progression, differentiation, apoptosis, immunity and epithelial-mesenchymal transition. There are three members in the mammalian RUNX family, each with distinct tissue expression profiles. RUNX genes play unique and redundant roles during development and adult tissue homeostasis. The ability of RUNX proteins to influence signaling...

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PMID: 36766749
DOI: 10.3390/cells12030408
PMCID: PMC9913995

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