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Article

Development and persistence of DAA resistance associated mutations in patients failing HCV treatment.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Nov 2015

Paolucci Stefania, Fiorina Loretta, Mariani Bianca, Landini Viviana, Gulminetti Roberto, Novati Stefano, Maserati Renato, Barbarini Giorgio, Bruno Raffaele, Baldanti Fausto

Abstract excerpt

BACKGROUND: Direct-acting antiviral agents (DAAs) combined with pegylated-interferon (PegIFN) and ribavirin (RBV) are still a standard treatment in patients with genotype 1HCV infection. However, virologic response could be impaired by baseline or early selection of resistant HCV strains. OBJECTIVES: The aim of this study was to determine the onset and persistence of resistance-associated mutations (RAMs) in the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26489401
DOI: 10.1016/j.jcv.2015.08.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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