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Article

Resistance to direct-acting antiviral agents: clinical utility and significance.

Current opinion in HIV and AIDS - 1 Sept 2015

Cento Valeria, Chevaliez Stephane, Perno Carlo Federico

Abstract excerpt

PURPOSE OF REVIEW: This article examines the dynamics and factors underlying hepatitis C virus (HCV) resistance, along with their impact on daily clinical management of HCV-infected patients. RECENT FINDINGS: Across available treatment-regimens, GT-3 is the most difficult-to-cure genotype, but also genotype-1a may show lower success-rates compared with genotype-1b. Natural resistance to NS3, NS5A and NS5B...

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Topics

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Share to Antiviral Agents
Share to Drug Resistance, Viral
Share to Genotyping Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepacivirus

Share to Hepatitis C, Chronic

Share to Microbial Sensitivity Tests

Share to Mutation, Missense

Share to Viral Nonstructural Proteins

Source

Identifiers

PMID: 26248125
DOI: 10.1097/COH.0000000000000177

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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