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Article

Resistance-associated substitutions and response to treatment in a chronic hepatitis C virus infected-patient: an unusual virological response case report.

BMC infectious diseases - 26 Apr 2021

Aldunate Fabián, Echeverría Natalia, Chiodi Daniela, López Pablo, Sánchez-Cicerón Adriana, Soñora Martín, Cristina Juan, Moratorio Gonzalo, Hernández Nelia, Moreno Pilar

Abstract excerpt

BACKGROUND: Direct-Acting agents (DAAs) target and inhibit essential viral replication proteins. They have revolutionized the treatment of Hepatitis C virus (HCV) infection reaching high levels of sustained virologic response. However, the detection of basal resistance-associated substitutions (RASs) to DAAs in naïve patients could be important in predicting the treatment outcome in some patients exhibiting...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33902462
DOI: 10.1186/s12879-021-06080-0
PMCID: PMC8077789

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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