Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lin-28 promotes symmetric stem cell division and drives adaptive growth in the adult Drosophila intestine.

Development (Cambridge, England) - 15 Oct 2015

Chen Ching-Huan, Luhur Arthur, Sokol Nicholas

Abstract excerpt

Stem cells switch between asymmetric and symmetric division to expand in number as tissues grow during development and in response to environmental changes. The stem cell intrinsic proteins controlling this switch are largely unknown, but one candidate is the Lin-28 pluripotency factor. A conserved RNA-binding protein that is downregulated in most animals as they develop from embryos to adults, Lin-28 persists in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Green Fluorescent Proteins
Share to Insulin
Share to Intestinal Mucosa

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to MicroRNAs

Share to Receptor Protein-Tyrosine Kinases

Share to Regeneration

Share to RNA-Binding Proteins

Share to Stem Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 26487778
DOI: 10.1242/dev.127951
PMCID: PMC4631770

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lin-28 promotes symmetric stem cell division and drives adaptive growth in the adult Drosophila intestine.PMID 26487778Read ↗

Genome-wide RNAi screen identifies networks involved in intestinal stem cell regulation in Drosophila.Semantic proximity Read ↗

MicroRNA profiling identifies novel regulators of stem cell function in the adult <i>Drosophila</i> intestineSemantic proximity Read ↗

Markers and Methods to Study Adult Midgut Stem Cells.Semantic proximity Read ↗

Identification and characterisation of cell intrinsic mechanisms regulating intestinal stem cell behaviour during acute damageSemantic proximity Read ↗

Intestinal epithelium-derived BMP controls stem cell self-renewal in Drosophila adult midgut.Semantic proximity Read ↗

Modulation of intestinal stem cell homeostasis by nutrients: a novel therapeutic option for intestinal diseasesSemantic proximity Read ↗

Re-entry into mitosis and regeneration of intestinal stem cells through enteroblast dedifferentiation in <i>Drosophila</i> midgutsSemantic proximity Read ↗

Nipped-A regulates intestinal stem cell proliferation in Drosophila.Semantic proximity Read ↗

A novel class of evolutionarily conserved genes defined by piwi are essential for stem cell self-renewal.Semantic proximity Read ↗

Direct control of germline stem cell division and cyst growth by neural insulin in Drosophila.Semantic proximity Read ↗

Identification of split-GAL4 drivers and enhancers that allow regional cell type manipulations of the <i>Drosophila melanogaster</i> intestineSemantic proximity Read ↗

Tuberous sclerosis complex and Myc coordinate the growth and division of Drosophila intestinal stem cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.