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Article

Nipped-A regulates intestinal stem cell proliferation in Drosophila.

Development (Cambridge, England) - 15 Feb 2017

Tauc Helen Marie, Tasdogan Alpaslan, Meyer Patrick, Pandur Petra

Abstract excerpt

Adult stem cells uphold a delicate balance between quiescent and active states, a deregulation of which can lead to age-associated diseases such as cancer. In Drosophila, intestinal stem cell (ISC) proliferation is tightly regulated and mis-regulation is detrimental to intestinal homeostasis. Various factors are known to govern ISC behavior; however, transcriptional changes in ISCs during aging are still unclear....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28196804
DOI: 10.1242/dev.142703

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