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Article

Diverse genetic architectures lead to the same cryptic phenotype in a yeast cross.

Nature communications - 1 Jun 2016

Taylor Matthew B, Phan Joann, Lee Jonathan T, McCadden Madelyn, Ehrenreich Ian M

Abstract excerpt

Cryptic genetic variants that do not typically influence traits can interact epistatically with each other and mutations to cause unexpected phenotypes. To improve understanding of the genetic architectures and molecular mechanisms that underlie these interactions, we comprehensively dissected the genetic bases of 17 independent instances of the same cryptic colony phenotype in a yeast cross. In eight cases, the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27248513
DOI: 10.1038/ncomms11669
PMCID: PMC4895441

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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