Histologically distinct neuroepithelial tumors with histone 3 G34  mutation are molecularly similar and comprise a single nosologic  entity.

doi:10.1007/s00401-015-1493-1

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Article

Histologically distinct neuroepithelial tumors with histone 3 G34 mutation are molecularly similar and comprise a single nosologic entity.

Acta neuropathologica - 1 Jan 2016

Korshunov Andrey, Capper David, Reuss David, Schrimpf Daniel, Ryzhova Marina, Hovestadt Volker, Sturm Dominik, Meyer Jochen, Jones Chris, Zheludkova Olga, Kumirova Ella, Golanov Andrey, Kool Marcel, Schüller Ulrich, Mittelbronn Michel, Hasselblatt Martin, Schittenhelm Jens, Reifenberger Guido, Herold-Mende Christel, Lichter Peter, von Deimling Andreas, Pfister Stefan M, Jones David T W

Abstract excerpt

In contrast to the relative morphological uniformity of histone H3 K27-mutant high-grade gliomas, H3 G34-mutant tumors present as a histopathologically heterogeneous group of neoplasms, with microscopic characteristics typical of either glioblastoma (GBM) or central nervous system primitive neuroectodermal tumors (CNS-PNET). In the current study, we performed an integrative clinical, histopathological and...

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PMID: 26482474
DOI: 10.1007/s00401-015-1493-1

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CCND2
MGMT
PDGFRA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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