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Article

Histone H3.3 G34-mutant Diffuse Gliomas in Adults.

The American journal of surgical pathology - 1 Feb 2022

Wang Leiming, Shao Liwei, Li Hainan, Yao Kun, Duan Zejun, Zhi Cheng, Song Shuangshuang, Cheng Ye, Wang Fuyu, Wang Wei, Piao Yueshan, Gui Qiuping, Lu Dehong, Qi Xueling, Teng Lianghong

Abstract excerpt

The characteristics of H3.3 G34-mutant gliomas in adults have yet to be specifically described. Thirty adults with H3.3 G34-mutant diffuse gliomas were retrospectively reviewed for clinical and pathologic information. Molecular profiling using next-generation sequencing was performed in 29 of the 30 H3.3 G34-mutant patients with 1 patient lacking available tumor samples, as well as 82 IDH/H3 wild-type adult...

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PMID: 34352809
DOI: 10.1097/PAS.0000000000001781

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