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Article

H3 G34-mutant high-grade glioma.

Brain tumor pathology - 1 Jan 2021

Lim Ka Young, Won Jae Kyung, Park Chul-Kee, Kim Seung-Ki, Choi Seung Hong, Kim Taemin, Yun Hongseok, Park Sung-Hye

Abstract excerpt

H3F3A G34 (H3.3 G34)-mutant high-grade gliomas (HGG) are rare, and newly recognized infiltrating gliomas of the cerebral hemisphere. Here, we report the clinicopathological and molecular characteristics of four H3.3 G34-mutant gliomas in terms of its biological behavior compared to those of glioblastomas (GBMs) and H3 K27M-mutant diffuse midline gliomas (DMGs) of our hospital. The median age of the four patients...

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PMID: 32995948
DOI: 10.1007/s10014-020-00378-8

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