Article
Association Tests of Multiple Phenotypes: ATeMP.
PloS one - 1 Jan 2015
Guo Xiaobo, Li Yixi, Ding Xiaohu, He Mingguang, Wang Xueqin, Zhang Heping
Abstract excerpt
Joint analysis of multiple phenotypes has gained growing attention in genome-wide association studies (GWASs), especially for the analysis of multiple intermediate phenotypes which measure the same underlying complex human disorder. One of the multivariate methods, MultiPhen (O' Reilly et al. 2012), employs the proportional odds model to regress a genotype on multiple phenotypes, hence ignoring the phenotypic...
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