Article
Experimental Evolution of Escherichia coli Persister Levels Using Cyclic Antibiotic Treatments.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2016
Van den Bergh Bram, Michiels Joran E, Michiels Jan
Abstract excerpt
Persister cells are difficult to study owing to their transient nature and their usually small number in bacterial populations. In the past, numerous attempts have been made to elucidate persistence mechanisms. However, because of the challenges involved in studying persisters and the clear redundancy in mechanisms underlying their generation, our knowledge of molecular pathways to persistence remains incomplete....
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