Article
Fighting bacterial persistence: Current and emerging anti-persister strategies and therapeutics.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy - 1 May 2018
Defraine Valerie, Fauvart Maarten, Michiels Jan
Abstract excerpt
In addition to the well-known strategies of antibiotic resistance and biofilm formation, bacterial populations possess an additional survival strategy to endure hostile environments or antibiotic exposure. A small fraction of transiently antibiotic-tolerant phenotypical variants, called persister cells, is capable of surviving treatment with high doses of antibiotics. When antibiotic pressure drops, persisters...
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