Article

Nasty Prophages and the Dynamics of Antibiotic-Tolerant Persister Cells

2017-10-09

Abstract excerpt

Bacterial persisters are phenotypic variants that survive antibiotic treatment in a dormant state and can be formed by multiple pathways. We recently proposed that the second messenger (p)ppGpp drives Escherichia coli persister formation through protease Lon and the activation of toxin-antitoxin (TA) modules. This model found support in the field, but also generated controversy as part of recent heated debates on...

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Literature Corpus work: 70c7b42a-230c-5473-9620-41e065cd55ea
DOI: 10.1101/200477

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