Article

A novel high-throughput assay identifies small molecules with activity against persister cells

2023-04-14

Abstract excerpt

Persister cells are a subpopulation of transiently antibiotic tolerant bacteria, which are believed to be the main cause of relapsing bacterial infections. Due to the importance of persister cells in human infections, there is a need for new antibiotics that kill bacteria independently of their activity. However, high-throughput assays to screen for drugs with such activity are missing. This is partly due to the t...

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Literature Corpus work: 91f52346-d3f4-51fa-89fb-04d0ec69c400
DOI: 10.1101/2023.04.13.536681

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