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Article

Integrative DNA methylation and gene expression analysis to assess the universality of the CpG island methylator phenotype.

Human genomics - 13 Oct 2015

Moarii Matahi, Reyal Fabien, Vert Jean-Philippe

Abstract excerpt

BACKGROUND: The CpG island methylator phenotype (CIMP) was first characterized in colorectal cancer but since has been extensively studied in several other tumor types such as breast, bladder, lung, and gastric. CIMP is of clinical importance as it has been reported to be associated with prognosis or response to treatment. However, the identification of a universal molecular basis to define CIMP across tumors has...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26463173
DOI: 10.1186/s40246-015-0048-9
PMCID: PMC4603341

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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