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Article

The Emergence of Pan-Cancer CIMP and Its Elusive Interpretation.

Biomolecules - 22 Nov 2016

Miller Brendan F, Sánchez-Vega Francisco, Elnitski Laura

Abstract excerpt

Epigenetic dysregulation is recognized as a hallmark of cancer. In the last 16 years, a CpG island methylator phenotype (CIMP) has been documented in tumors originating from different tissues. However, a looming question in the field is whether or not CIMP is a pan-cancer phenomenon or a tissue-specific event. Here, we give a synopsis of the history of CIMP and describe the pattern of DNA methylation that defines...

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Identifiers

PMID: 27879658
DOI: 10.3390/biom6040045
PMCID: PMC5197955

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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