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Article

Polygenic susceptibility to testicular cancer: implications for personalised health care.

British journal of cancer - 17 Nov 2015

Litchfield Kevin, Mitchell Jonathan S, Shipley Janet, Huddart Robert, Rajpert-De Meyts Ewa, Skakkebæk Niels E, Houlston Richard S, Turnbull Clare

Abstract excerpt

BACKGROUND: The increasing incidence of testicular germ cell tumour (TGCT) combined with its strong heritable basis suggests that stratified screening for the early detection of TGCT may be clinically useful. We modelled the efficiency of such a personalised screening approach, based on genetic risk profiling in combination with other diagnostic tools. METHODS: We compared the number of cases potentially...

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Source

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Identifiers

PMID: 26461055
DOI: 10.1038/bjc.2015.334
PMCID: PMC4815881

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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