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Article

Rescuing lymphocytes from HLA-G immunosuppressive effects mediated by the tumor microenvironment.

Oncotarget - 10 Nov 2015

Wu Danli, Kuiaste Isere, Moreau Philippe, Carosella Edgardo, Yotnda Patricia

Abstract excerpt

Several studies have demonstrated that the antitumor activities of both T and natural killer (NK) effector populations are limited by the immunosuppressive strategies of tumors. In several malignant transformations, the expression of HLA-G by tumor cells rises dramatically, rendering them strongly immunosuppressive. In this study, we postulated that the absence of HLA-G receptors would prevent the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA-G Antigens

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Identifiers

PMID: 26460949
DOI: 10.18632/oncotarget.6044
PMCID: PMC4741936

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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