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Article

Human Leukocyte Antigen–G and Cancer Immunoediting

1 Feb 2008

Abstract excerpt

Immunosurveillance is an extrinsic mechanism of cancer suppression that eliminates nascent tumors. However, the selection imposed by immunosurveillance can drive tumor evolution and the emergence of clinically apparent neoplasms. Mechanisms of immune escape acquired by less immunogenic variants during this process, termed immunoediting, may contribute significantly to malignant progression. In this review, we...

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PMID: 18245459
DOI: 10.1158/0008-5472.can-07-2704

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