Article
Gene-based analysis of the fibroblast growth factor receptor signaling pathway in relation to breast cancer in African American women: the AMBER consortium.
Breast cancer research and treatment - 1 Jan 2016
Ruiz-Narváez Edward A, Haddad Stephen A, Lunetta Kathryn L, Yao Song, Bensen Jeannette T, Sucheston-Campbell Lara E, Hong Chi-Chen, Haiman Christopher A, Olshan Andrew F, Ambrosone Christine B, Palmer Julie R
Abstract excerpt
We conducted gene-based analysis in 26 genes in the FGFR signaling pathway to identify genes carrying genetic variation affecting risk of breast cancer and the specific estrogen receptor (ER) subtypes. Tagging single-nucleotide polymorphisms (SNPs) for each gene were selected and genotyped on a customized Illumina Exome Array. Imputation was carried out using 1000 Genomes haplotypes. The analysis included 3237...
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