Article
Genetic susceptibility loci for subtypes of breast cancer in an African American population.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2013
Palmer Julie R, Ruiz-Narvaez Edward A, Rotimi Charles N, Cupples L Adrienne, Cozier Yvette C, Adams-Campbell Lucile L, Rosenberg Lynn
Abstract excerpt
BACKGROUND: Most genome-wide association studies (GWAS) have been carried out in European ancestry populations; no risk variants for breast cancer have been identified solely from African ancestry GWAS data. Few GWAS hits have replicated in African ancestry populations. METHODS: In a nested case-control study of breast cancer in the Black Women's Health Study (1,199 cases/1,948 controls), we evaluated index...
Topics
- Adult
- Black or African American
- Age Distribution
- Aged
- Breast Neoplasms
- Case-Control Studies
- Confidence Intervals
- Female
- Genetic Loci
- Genetic Predisposition to Disease