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Article

Convergent phosphomodulation of the major neuronal dendritic potassium channel Kv4.2 by pituitary adenylate cyclase-activating polypeptide.

Neuropharmacology - 1 Feb 2016

Gupte Raeesa P, Kadunganattil Suraj, Shepherd Andrew J, Merrill Ronald, Planer William, Bruchas Michael R, Strack Stefan, Mohapatra Durga P

Abstract excerpt

The endogenous neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) is secreted by both neuronal and non-neuronal cells in the brain and spinal cord, in response to pathological conditions such as stroke, seizures, chronic inflammatory and neuropathic pain. PACAP has been shown to exert various neuromodulatory and neuroprotective effects. However, direct influence of PACAP on the function of...

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Identifiers

PMID: 26456351
DOI: 10.1016/j.neuropharm.2015.10.006
PMCID: PMC4681664

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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