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Article

Functional and molecular diversity of PACAP/VIP receptors in cortical neurons and type I astrocytes.

The European journal of neuroscience - 1 Aug 1999

Grimaldi M, Cavallaro S

Abstract excerpt

In the present study we determined the mRNA-expression of pituitary adenylate cyclase activating polypeptide (PACAP)/vasoactive intestinal peptide (VIP) receptors in primary cultures of rat cortical neurons and type I astrocytes, and investigated the effects of PACAP38 on adenylyl cyclase, inositol phospholipid hydrolysis and intracellular calcium homeostasis. PACAP38 elicited a concentration-dependent (1 nM-100...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10457173
DOI: 10.1046/j.1460-9568.1999.00693.x

Genes

VIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Functional and molecular diversity of PACAP/VIP receptors in cortical neurons and type I astrocytes.PMID 10457173Read ↗

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Studying complex system: calcium oscillations as attractor of cell differentiation.Semantic proximity Read ↗

New Insights into the Central PACAPergic System from the Phenotypes in PACAP‐ and PACAP Receptor‐Knockout MiceSemantic proximity Read ↗

Pituitary adenylate cyclase-activating polypeptides directly stimulate sympathetic neuron neuropeptide Y release through PAC(1) receptor isoform activation of specific intracellular signaling pathways.Semantic proximity Read ↗

Pituitary adenylate cyclase-activating polypeptides, PACAP-38 and PACAP-27, regulation of sympathetic neuron catecholamine, and neuropeptide Y expression through activation of type I PACAP/VIP receptor isoforms.Semantic proximity Read ↗

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