Article
Crystal structure of the bacteriophage P2 integrase catalytic domain.
FEBS letters - 30 Nov 2015
Skaar Karin, Claesson Magnus, Odegrip Richard, Högbom Martin, Haggård-Ljungquist Elisabeth, Stenmark Pål
Abstract excerpt
Bacteriophage P2 is a temperate phage capable of integrating its DNA into the host genome by site-specific recombination upon lysogenization. Integration and excision of the phage genome requires P2 integrase, which performs recognition, cleavage and joining of DNA during these processes. This work presents the high-resolution crystal structure of the catalytic domain of P2 integrase, and analysis of the...
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