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Article

Dimerization of bacteriophage P2 integrase is not required for binding to its DNA target but for its biological activity.

Gene - 3 Jan 2005

Frumerie Clara, M Eriksson Jesper, Dugast Marc, Haggård-Ljungquist Elisabeth

Abstract excerpt

Coliphage P2 integrates into the host chromosome upon lysogenization via site-specific recombination mediated by the phage integrase (Int). P2 integrase belongs to the tyrosine family of recombinases. In this work, it is shown that P2 integrase forms dimers but not oligomers in the absence of its DNA target. Furthermore, the C-terminal end of the protein and amino acid (aa) E197 have been found to be involved in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Electrophoresis, Polyacrylamide Gel

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Source

Identifiers

PMID: 15656988
DOI: 10.1016/j.gene.2004.09.026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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