Article
Recombination directionality factor gp3 binds ϕC31 integrase via the zinc domain, potentially affecting the trajectory of the coiled-coil motif.
Nucleic acids research - 16 Feb 2018
Fogg Paul C M, Younger Ellen, Fernando Booshini D, Khaleel Thanafez, Stark W Marshall, Smith Margaret C M
Abstract excerpt
To establish a prophage state, the genomic DNA of temperate bacteriophages normally becomes integrated into the genome of their host bacterium by integrase-mediated, site-specific DNA recombination. Serine integrases catalyse a single crossover between an attachment site in the host (attB) and a phage attachment site (attP) on the circularized phage genome to generate the integrated prophage DNA flanked by...
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