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Article

Screening Key Sites of Class 2 Integron Integrase that Impact Recombination Efficiency.

Current microbiology - 6 May 2024

Wang Xiaotong, Dai Yueru, Kong Nana, Cao Mei, Zhang Long, Wei Quhao

Abstract excerpt

By capturing and expressing exogenous resistance gene cassettes through site-specific recombination, integrons play important roles in the horizontal transfer of antimicrobial resistant genes among bacteria. The characteristics of integron integrase make it to be a potential gene editing tool enzyme. In this study, a random mutation library using error-prone PCR was constructed, and amino acid residues mutants...

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Identifiers

PMID: 38710822
DOI: 10.1007/s00284-024-03674-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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