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Article

Heterogeneous computing architecture for fast detection of SNP-SNP interactions.

BMC bioinformatics - 25 Jun 2014

Sluga Davor, Curk Tomaz, Zupan Blaz, Lotric Uros

Abstract excerpt

BACKGROUND: The extent of data in a typical genome-wide association study (GWAS) poses considerable computational challenges to software tools for gene-gene interaction discovery. Exhaustive evaluation of all interactions among hundreds of thousands to millions of single nucleotide polymorphisms (SNPs) may require weeks or even months of computation. Massively parallel hardware within a modern Graphic Processing...

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PMID: 24964802
DOI: 10.1186/1471-2105-15-216
PMCID: PMC4230497

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