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Article

Epistasis detection on quantitative phenotypes by exhaustive enumeration using GPUs.

Bioinformatics (Oxford, England) - 1 Jul 2011

Kam-Thong Tony, Pütz Benno, Karbalai Nazanin, Müller-Myhsok Bertram, Borgwardt Karsten

Abstract excerpt

MOTIVATION: In recent years, numerous genome-wide association studies have been conducted to identify genetic makeup that explains phenotypic differences observed in human population. Analytical tests on single loci are readily available and embedded in common genome analysis software toolset. The search for significant epistasis (gene-gene interactions) still poses as a computational challenge for modern day...

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PMID: 21685073
DOI: 10.1093/bioinformatics/btr218
PMCID: PMC3117340

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