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Article

High-resolution Melting Analysis for Gene Scanning of Adenomatous Polyposis Coli (APC) Gene With Oral Squamous Cell Carcinoma Samples.

Applied immunohistochemistry & molecular morphology : AIMM - 1 Feb 2016

Chang Ya-Sian, Lin Chien-Yu, Yang Shu-Fen, Ho Cheng Mao, Chang Jan-Gowth

Abstract excerpt

BACKGROUND: There have been many different mutations reported for the large adenomatous polyposis coli (APC) tumor suppressor gene. APC mutations result in inactivation of APC tumor suppressor action, allowing the progression of tumorigenesis. The present study utilized a highly efficient method to identify APC mutations and investigated the association between the APC genetic variants Y486Y, A545A, T1493T, and...

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Source

Identifiers

PMID: 26447891
DOI: 10.1097/PAI.0000000000000158

Genes

APC

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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