Article
Detection of SF3B3 gene mutations in oral cancer by high resolution melting analysis.
Clinical laboratory - 1 Jan 2014
Chang Chun-Chi, Chang Ya-Sian, Chan Wen-Ling, Yeh Kun-Tu, Wei Ren-Jeng, Chang Jan-Gowth
Abstract excerpt
BACKGROUND: There is a high prevalence of oral cancer in Taiwan, which is associated with betel quid chewing. Gene encoding splicing factors, especially splicing factor 3b subunit 1 (SF3B1), have been shown to be the most highly mutated in various hematological malignancies and have a great influence on clinical outcomes. However, few splicing targets have been identified for oral cancer. The aim of this study...
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