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Article

Predicting functional regulatory SNPs in the human antimicrobial peptide genes DEFB1 and CAMP in tuberculosis and HIV/AIDS.

Computational biology and chemistry - 1 Dec 2015

Flores Saiffe Farías Adolfo, Jaime Herrera López Enrique, Moreno Vázquez Cristopher Jorge, Li Wentian, Prado Montes de Oca Ernesto

Abstract excerpt

Single nucleotide polymorphisms (SNPs) in transcription factor binding sites (TFBSs) within gene promoter region or enhancers can modify the transcription rate of genes related to complex diseases. These SNPs can be called regulatory SNPs (rSNPs). Data compiled from recent projects, such as the 1000 Genomes Project and ENCODE, has revealed essential information used to perform in silico prediction of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26447748
DOI: 10.1016/j.compbiolchem.2015.09.002

Genes

CAMP
DEFB1
BRCA1
EBF1
EGR1
FOXP2
JUN
KLF5
NFKB1
RUNX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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