Article
First insights into the molecular basis association between promoter polymorphisms of the IL1B gene and Helicobacter pylori infection in the Sudanese population: computational approach.
BMC microbiology - 7 Jan 2021
Idris Abeer Babiker, Idris Einas Babiker, Ataelmanan Amany Eltayib, Mohamed Ali Elbagir Ali, Osman Arbab Bashir M, Ibrahim El-Amin Mohamed, Hassan Mohamed A
Abstract excerpt
BACKGROUND: Helicobacter pylori (H. pylori) infects nearly half of the world's population with a variation in incidence among different geographic regions. Genetic variants in the promoter regions of the IL1B gene can affect cytokine expression and creates a condition of hypoacidity which favors the survival and colonization of H. pylori. Therefore, the aim of this study was to characterize the polymorphic sites...
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