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Article

A post-GWAS analysis of predicted regulatory variants and tuberculosis susceptibility.

PloS one - 1 Jan 2017

Uren Caitlin, Henn Brenna M, Franke Andre, Wittig Michael, van Helden Paul D, Hoal Eileen G, Möller Marlo

Abstract excerpt

Utilizing data from published tuberculosis (TB) genome-wide association studies (GWAS), we use a bioinformatics pipeline to detect all polymorphisms in linkage disequilibrium (LD) with variants previously implicated in TB disease susceptibility. The probability that these variants had a predicted regulatory function was estimated using RegulomeDB and Ensembl's Variant Effect Predictor. Subsequent genotyping of...

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Identifiers

PMID: 28384278
DOI: 10.1371/journal.pone.0174738
PMCID: PMC5383035

Genes

ACACA
IFNGR2
MARCO
NISCH
TLR10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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